|
|
$BK\G/EY5>@7;` $B:G6a%^%9%4%_$,7vEA$9$kG>HhO+:>5=(B $B$3$l$C$F%3%m%J%o%/%A%s8e0d>I$^$s$^(B $BJ8A/L@!u<+L1E^$N65$((B $B"#F|K\L1B2$HF|K\$N9q$OLG$S$F$b4Z9q$O;D$5$J$1$l$P$J$i$J$$$N$@!#(B $B"#$3$3F|K\$N@hAD$?$A$,@$$NCf$G8@$($P1e=2$@!#F|K\$N9q$,1e=2$@!#(B $B"#F|K\$N8=:_$N9DB@;R$NIW?M$,2?$N $B"#J?$Y$C$?$$E79D!"L5NO$JE79D$@!#(B $B"#F|K\$NE79D$b $B4ZDa;R!u8xL@E^$N65$((B $B"#!JF|K\?M$O!K?M4VE*$K9M$($l$P $BE}0l652q65AD!V=>730V0BIX;v7o$,$"$C$?$N$G!"F|K\?M$N=w$O4Z9q$N8p?)$H7k:'$7$F$b46 $B!VEg9q$O=w@-$N1"It!W(B $B!VF|K\$OIW$G$"$k4Z9q$KJ{$2$J$1$l$P$J$i$J$$!W(B $B@;K\(B3000$BK|1_!"@b65K\%;%C%H(B430$BK|1_!"7k:'<0(B140$BK|1_!"(B $B@hAD$N --------------------------------------------- $B;`K4?t$,%o%/%A%s@\ --------------------------------------------- $BD9Hx0e;U%A%c%s%M%k(B https://nico.ms/sm41181636 $B%o%/%A%s8e0d>I $B$"$J$?$NBND4ITNI$O!"%3%m%J%o%/%A%s$,860x$+$b$7$l$J$$!W(B --------------------------------------------- $B%o%/%A%s@\ --------------------------------------------- $B$3$l@\ $B=E>I(BCOVID-19$B45 --------------------------------------------- $B$J!) $B%o%/%A%s$G2rG.DCDK:^$,Ht$V$h$&$KGd$l$?$1$I$"$s$J$N%P%+%9%+0{$s$G$$$$$b$s$J$N!)(B --------------------------------------------- $B$?$^$K0{$`$J$i$$$$$,!">oMQ$9$k$H?UB!$,$d$i$l$k!#(B --------------------------------------------- $B%9%Q%$%/"*%j%]B?E|$/$C$D$/"*1j>I"*%_%/%m%0%j%"(BTNF-$B&AJ,Hg"*F,DK!"$&$D!"0`=L!"%V%l%$%s%U%)%0(B $B%9%Q%$%/%?%s%Q%/ https://pubmed.ncbi.nlm.nih.gov/33295606/ $B:Y6]46@w$GG>5!G=$,JQ2=$9$k;EAH$_$r2rL@(B $B!]%_%/%m%0%j%"$OBgG>$N?@7P3hF0$rDc2<$5$;$k!](B https://www.kyoto-u.ac.jp/ja/research-news/2022-02-17 --------------------------------------------- $BFs2sL\$N%b%G%k%J$N=j0Y$G!">e0vF,1j$+I{I!9P1j$_$?$$$JF,DK$,$:$C$HB3$$$F$k$h!#(B $B%m%-%=%K%s$,$[$\>oHwLt$K$J$C$?!#(B $B0x$_$K;02sL\0J9_$O%U%!%$%6! $B$^$!BN $B%o%/%A%s$NI{H?1~$O#2F|$K8B$i$l$k$1$I(B $B $B<+J,$@$1$+$b$7$l$s$1$I!#(B $B:#8e!"2~A1$5$l$F$$$/$s$+$J(B --------------------------------------------- $B%S%?%_%s$H$?$s$Q$/ 3$B2s$H$bI{:nMQ$,A4A3$G$J$+$C$?$h(B $B$G$b0l1~O"5Y$H$C$?$7DCDK:^$H$+%]%+%j$H$+%+%C%WLM$H$+(B $B?'!9=`Hw$b$7$F$?$+$i$J$s$+B;$7$?5$$b$9$k(B $B%?%$%l%N!<%k https://www.biorxiv.org/content/10.1101/2022.04.19.488806v1.full $B$3$N8&5f$N%G!<%?$O!"%9%Q%$%/%?%s%Q%/ --------------------------------------------- https://molecular-cancer.biomedcentral.com/articles/10.1186/s12943-020-01157-x >$B%U%'%m%H!<%7%9$,!"?46Z>I!" --------------------------------------------- https://twitter.com/wolfhopp7/status/1581102109314863104 $B@tBgDE;T5D2q$K$F!"(B5$B:P!A(B11$B:P$N(B2$B2s@\ --------------------------------------------- BA.4-5$BBP1~%o%/%A%s$O%^%&%9$@$1$N<#837k2L$7$+$J$$HsNW>2%G!<%?!#(B $B%R%H$G$NNW>2;n83%G!<%?$OF@$i$l$F$$$J$$!#(B https://www.mhlw.go.jp/content/10900000/000998596.pdf --------------------------------------------- $B#9%v7nA0$K@\ $B$=$7$F$=$N%9%Q%$%/%?%s%Q%/ $B$o$6$o$6Ip4A7?$r:.$<9g$o$;$k0UL#$,$o$+$i$s$N$@$,2?$+M}M3$,$"$k$N$+$J(B --------------------------------------------- $B#22A%o%/%A%s$rBG$D?M$O2a5n$K2?EY$bIp4A7?%o%/%A%s$rBG$C$F$?4X78>eIp4A7?%9%Q%$%/$,!"$"$A$3$A$N7r>o$JB!4o$N:YK&$K$/$C$D$$$?$^$^$K$J$C$F$$$F%9%Q%$%/$,$/$C$D$/$?$S$K!"LH1VH?1~$,!"$=$N7r>o$JB!4o$N:YK&$=$N$b$N$rGK2u$7$h$&$H$9$k!J(Bepitope spreading)$B$N$rIp4A7?(BTreg$B$K$h$kLH1VM^@)$K$h$C$FM^$(9~$s$G$$$?$o$1$h(B $B$3$N>uBV$G!"?7$?$K(BBA1($B$^$?$O(BBA5)$B%9%Q%$%/$,CmF~$5$l$k$H(BBA1$B%9%Q%$%/$bB!4o$N:YK&$K$/$C$D$$$F!":F$SLH1VH?1~$,$=$NB!4o$N:YK&$rGK2u$7$h$&$H$9$k$,!"$3$N$H$-!"$=$NB!4o$N:YK&$K$O(BBA1$B%9%Q%$%/$N$_$J$i$:!"Ip4A7?%9%Q%$%/$b;D$C$F$k$?$a(BBATreg$B$HIp4A7?(BTreg$B$N#2 $B$7$?$,$C$F!"%o%/%A%s@\ $B!V%o%/%A%s$,860x$GK4$/$J$C$?$H9q$KI,$:G'$a$F$b$i$$$?$$!D!W@\ https://asahi.5ch.net/test/read.cgi/newsplus/1666307380/ --------------------------------------------- $B<+8J@UG$$@$h$J(B $BD62a;`K4:#$N;~E@$G(B8$B7n$N;~E@$G(B7$BK|?M$@$C$1$+!)(B $B$$$A$$$A6bJ'$C$F$?$i$-$j$J$$$o(B --------------------------------------------- $B:#G/A0H>$N9qFb!VD62a;`K4!W!":GBg(B4$BK|(B6000$B?M!!%3%m%J8e$G:GB?(B https://mainichi.jp/articles/20221011/k00/00m/040/103000c --------------------------------------------- $B8|@8O+F/>J!&%o%/%A%sJ,2J2q!!(B2022$BG/(B10$B7n(B7$BF|(B $B!V%R%H$G$N(B2$B2A(B($B5/8;3t(B/$B%*%_%/%m%s3t(BBA.4-5)$B%o%/%A%s$NNW>2;n83%G!<%?$O(B $BF@$i$l$F$$$J$$!#!W(B https://www.mhlw.go.jp/content/10900000/000998596.pdf --------------------------------------------- $B26$NJl$O4b$@$C$?$s$@$,(B $B%o%/%A%s@\ --------------------------------------------- $BL?7|$1$G $B8=;~E@$G$OL)Ls$b$"$k$7F|K\@/I\$,>! $B>-Mh$K8~$1$FL5M}%2!<$G$b@=B$85$KG'$a$5$;$l$P$I$&!)>P(B --------------------------------------------- $B%o%/%A%s$,860x$G;`$s$@$G$"$m$&O7?M$C$F $BD6855$$@$C$?$N$K$"$^$j$K$b5^7c$K $B4pAC<@45$"$k?M$O$b$A$m$s(B80$BBe0J9_$NO7?M$J$s$+$,BG$D$N$O5U$K4m812a$.$k$H;W$&(B --------------------------------------------- $B$h$[$I6/$$0U;V$G5qH]$7$J$$8B$j(B $BED $B!V;&?M%o%/%A%s!W$J$s$F%U%l!<%:$,Ht$S8r$&;~E@$G2{5?E*$K8+$k$N$,Ev$?$jA0$d$7$N(B($B>P(B) $B$=$b$=$b46@w3HBg$7$F$$$k;~4|$K(BGOTO$B$d$k$h$&$J9q$r?.MQ$9$k$J(B --------------------------------------------- $B8e=P$7$GLt32$O$$$D$b$N%Q%?!<%s(B $B?eKsIB$9$iH/@8$+$i(B12$BG/8e$K8|@8>J$,8x32G'Dj$7$?(B $BH/@8$+$iH>@$5*0J>e7P$C$F$b:[H=$,B3$$$F$$$/(B $B0dEA;R$G;RB9$K$b1F6A$"$k$+$i$M(B $B:#2s$N(BmRNA$B%o%/%A%s$OCfD94|$N<#83$r40A4$KL5;k$7$F!"6[5^;~;HMQ5v2D$G>5G'$7$F$$$k$+$i(B --------------------------------------------- |